Such a pathological condition as edema is a fairly common phenomenon. If you have edema a large amount of liquid accumulates in the tissues of the organism. And very often people with heart disease suffer of edema. Why is this happening? It is generally known that the kidneys primarily support the normal body fluid and electrolyte balance. And the adrenal glands produce a special hormone aldosterone, the level of which greatly increases the heart failure. As a result kidneys retain salt and water in excessive amounts. Concurrently, level of potassium in the blood is reduced, which stimulates the removal of excess fluid from the body.
To combat the edema, doctors use various drugs, one of which is Aldactone. Instructions for use characterizes this medicine as a diuretic, supporting the body’s potassium levels.
Aldactone is prescribed to relieve edema, arising from hypertension, chronic heart failure, ascites (hepatic cirrhosis), problems with the endocrine system (hirsutism, polycystic of ovary Conn’s syndrome). Indications for use of this drug are cerebral edema, paroxysmal paralysis that occurs as a result of calcium deficiency in the body. Furthermore, it is used to treat myasthenia gravis as an additional active medicament drug.
Aldactone dosage and duration of administration depend on the nature of the disease, accompanied by edema. In particular, adults with heart failure is first administered 25 mg of the drug. This is an initial daily dose. Then a maintenance dose is prescribed that the doctor determines individually for each patient. The initial dose during essential hypertension is 50 – 100 mg per day, and during hepatic cirrhosis is 100 – 400 milligrams. For children older than 3 years, the daily dose is determined by the rate of 3 milligrams per kilogram of body weight.
During the use of Aldactone you should consider a contraindication to its acceptance. These ones include hyperkalemia, acute and chronic kidneys failure, hyponatremia, anuria, Addison’s disease. It is forbidden to take the drug in case of hypersensitivity to its components, for women during pregnancy and breastfeeding and children under 3 years old.
Aldactone can cause side effects. Sometimes there are nausea, leg cramps, confusion, dizziness. The endocrine system can respond by menstrual irregularities, decreased of libido, pain in the breast, and hematopoietic system – thrombocytopenia, agranulocytosis, leukopenia. Also, we can notice the cases of allergic and dermatological symptoms: itching, rash, hypertrichosis, alopecia.