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Orlistat

Orlistat provides new approach to the effective weight loss. Orlistat is a specific and long-acting inhibitor of stomach and pancreatic lipase prevents the splitting and consequent absorption of food fats. The drug acts within the gastrointestinal tract and doesn’t have a systemic effect. The dose of drug is 120 mg with the main meals or no later than 1 hour after eating.

In contrast to the food additives, Orlistat is an official medicine. The action of Xenical is based on its ability to hold up the action of substance called lipase. Lipase is produced in the human’s pancreas and promotes the splitting and absorption of fat, coming to the gastrointestinal tract as a part of consumed meal. As a result of taking Xenical, the consumed fat is absorbed 30% worse.

So, 30% of consumed fat neither splits into its components, nor absorbs in the intestines. Instead, it goes through the gastrointestinal tract without delay and is deuced with excrements.

We shall notice once again- Orlistat acts only on fats! That’s why it can be prescribed only if the major part of your diet consists mainly of animal fats. Orlistat has no effect on the absorption of carbohydrates and proteins.

So, if the animal fats don’t form the major part of your diet, it makes the use of Orlistat completely worthless. There will be no effect.

So, in this case, Orlistat has nothing to do with this. You can lose weight because you start to follow a low-calorie diet.

However, that’s not all. Let’s say, you really eat a lot of fats (which you shouldn’t do, as after the refuse of Orlistat, sticking to the usual diet, you’ll bring your kilos back very soon) and the intake of Xenical helps you to lose weight.

Orlistat is a medicine of peripheral action, aimed at the key factor of obesity- food fats. Orlistat is a powerful, specific and really long-acting inhibitor of stomach and pancreatic lipases, preventing the splitting and consequent absorbing of food fats.

The side effects include: fat stool, frequent defecating, urges to defecate, oily secretions from the back end. The side effects are usually slightly pronounced and appear in the first 2- 3 weeks of treatment. They are connected with the mechanism of action of the medicine. So, by the appropriate correction of eating (fat intake must be less than 30% from daily calorie intake) they pass on their own.

An important thing is a study of interactions between Orlistat and other medicines, as the people with obesity, having associated diseases and complications, take any other drugs. During the study of pharmacokinetics of Orlistat no signs of its interrelation with anti-diabetic and anti- hypertensive drugs have been found.

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