Among the huge number of medicines that lower the pressure, the big distribution have received ACE inhibitors (angiotensin converting enzyme). One of the representatives of this group is the drug Altace. Instructions for use notes that the ACE inhibitor has not only a hypotensive (pressure reducing) and cardioprotective activity. Such properties of medications allow to use it, except for treatment of hypertension, in the treatment of ischemic heart disease and chronic heart failure.
Active current component of Altace drug is substance ramipril. In the treatment of hypertension ramipril helps to reduce systolic and diastolic blood pressure, but the frequency of heart rate isn’t increased. This medicament has the ability to block the angiotensin, converting enzyme in the blood and muscle cells of vascular smooth muscle. As a result of such exposure peripheral vascular resistance is reduced, eliminated cramps, blood pressure decreases. In addition, in patients with hypercholesterolemia Altace is capable of dissolving in the walls of blood vessels cholesterol deposits and blood clots, so, provide angioprotective action. Finally, people who have suffered a myocardial infarction, the drug reduces the area of distribution of necrosis of heart muscle tissue, thereby preventing the recurrence of this life-threatening disease.
Thus, indications for use of the drug Altace are treatment of hypertension, chronic and congestive heart failure, heart disease and also nephropathy (kidney function violation). As a preventive measure the medicament is used to improve blood circulation and cerebral infarction, preventing the development of stroke and heart attack.
The dosage and duration of treatment is appointed by doctor. According to the instructions, during the treatment of the underlying disease (hypertension) you should take at first times 2.5 milligrams of the drug a day. Then, every 2 – 3 weeks dosage is increased until the desired therapeutic effect will occur. The average daily maintenance dose: 2.5 – 5 milligrams.
Of course, it is required to take into account contraindications of receiving the drug Altace. Do not take this remedy if you have the serious violations of hepatic function, renal artery stenosis, systemic of lupus erythematosus, primary hyperaldosteronism, angioedema, violation of balance of potassium and sodium in the blood. This medication is nit recommended for people with individual intolerance to components that can cause allergic reactions. Medications is contraindicated to children under the age of 15 years, for women during pregnancy and breast-feeding a baby. The drug is prescribed with caution for patients suffering from diabetes, as well as elderly people.
The drug Altace also has side effects. Instructions for use notes that sometimes patients complain on a sharp decrease of blood pressure, leading to arrhythmia, tachycardia, collapse. Perhaps the emergence of negative phenomena such as weakness, dizziness, fatigue, drowsiness, anxiety, loss of appetite, nausea, thirst, pain in the abdomen. Genito-urinary system can respond by edema of extremities, proteinuria, decreased of libido, impotence.