Isotretinoin is a medical preparation designated for treatment of serious displays of acne, which do submit to treatment by other means, including antibiotics. Nevertheless, Isotretinoin may cause serious by-effects. Before the beginning of application of Isotretinoin consult with the doctor to find out a current condition of disease, a possible positive effect from treatment by Isotretinoin, and also possible by-effects. Your doctor will ask you to familiarize with and sign the document, confirming that you realize the serious risk connected with treatment by Isotretinoin .
Some patients suffer symptoms of depression (feeling of despondency, irritability, undue fatiguability, infringement of concentration of attention and loss of appetite), and also ideas on a suicide during treatment or after the termination of reception Isotretinoin . Immediately inform the doctor if you will have attributes of depression or an idea of suicide during treatment or soon after the termination of reception Isotretinoin .
Do not accept the vitamin additives containing vitamin A, during treatment with Isotretinoin . It can lead to strengthening of collateral actions.
Do not hand over donor blood during the reception Isotretinoin and not less than month after the termination of reception of a preparation. The blood which has been handed over during reception Isotretinoin may be poured to the pregnant woman and may harm its child.
Do not apply wax procedures to removal of hair on your skin, and also refrain from grinding procedures your skin (such as dermabrasion or laser procedures) during reception of Isotretinoin and within six months after its termination to avoid occurrence of scars.
Avoid being under sunlight, and also influences of ultra-violet beams during the reception Isotretinoin . Isotretinoin can raise sensitivity of skin to solar beams that may lead to serious solar burns.
Be careful while driving the car at night. Isotretinoin can affect ability to see at night. Deterioration of night sight may suddenly come.
Accept all Isotretinoin that was prescribed to you, even if improvement of your condition is observed. In the beginning of reception of a preparation deterioration of acne is possible, but after that an improvement should be observed. To obtain the best results finish the full course of a preparation, prescribed by the doctor. Probably it is required more than one course of treatment with Isotretinoin . What is Isotretinoin ?
Isotretinoin is one of the forms of vitamin A. It reduces quantity of the skin fat developed by sebaceous glands, and also accelerates natural regeneration of a skin.
Isotretinoin is used for treatment of strong displays of acne, which do not submit to treatment by other preparations, including antibiotics.
Isotretinoin may be applied to other purposes, which are not specified in the instruction on application.
What should I discuss with the doctor before to buy Isotretinoin?
Before the beginning of application Isotretinoin inform the doctor, if you have:
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- diabetes;
- individual or hereditary history of mental problems, including depression, propensity to a suicide, any forms of a psychosis (loss of contact with reality, visual and acoustical hallucinations);
- asthma;
- cardiovascular diseases;
- osteoporosis (loss of bone weight) or porosity of bones;
- nervous anorexia;
- a high level of cholesterol or triglyceride in blood; or
- disease of liver.
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If Isotretinoin is not good for you, or you may need correction of a doze or special supervision during treatment, if you suffer from any of the set forth above diseases.
Do not accept Isotretinoin during pregnancy and do not become pregnant during all rate of its application, and also within a month after you have stopped to accept a preparation. Isotretinoin on a degree of risk at pregnancy concerns to category X on classification FDA (Food and Drug Administration). It means that Isotretinoin can cause developmental anomalies of a fetus. It also can become the reason of an abortion, premature birth or death of the child. You should hand over the test for pregnancy and be convinced of negative result before you and your doctor will solve the problem of expediency of prescribing of Isotretinoin . You should hand over the repeated test for pregnancy and be convinced of its negative result within the first 5 days menstrual cycle before the beginning of acceptance of a preparation. Two reliable ways of contraception should be used simultaneously (if as contraception the method of abstention is not used or to you have not been made hysterectomy) within a month prior to the beginning of reception of Isotretinoin , during treatment with Isotretinoin and at least within 1 one month after the termination of treatment by this preparation. Also you will need to hand over the test for pregnancy monthly. Your doctor will discuss with you and will give you the information on possible methods of contraception, possible failures in contraception, and also importance of use contraceptive means during reception of Isotretinoin . If you have become pregnant, have stopped to accept contraceptive means or have passed a menstrual cycle, stop the application of Isotretinoin and inform the doctor.
It is not established authentically, whether Isotretinoin is transferable in chest milk. If you breast-feed, do not accept Isotretinoin without preliminary consultation of your doctor.
The way of application
Isotretinoin should be applied in exact conformity with recommendations of the doctor. For specification of instructions to application address to a pharmacist, a nurse or a doctor.
Isotretinoin is applied for treatment of heavy forms nodular-gangliac acne which do not submit to treatment by other preparations, including antibiotics. Nevertheless, Isotretinoin has a number of serious by-effects. Before the beginning of reception of Isotretinoin consult with the doctor and discuss a possible positive effect from treatment by the given preparation, and also its possible by-effect. Your doctor will ask you to familiarize and sign the document confirming, that you realize the serious risk connected with treatment Isotretinoin .
You’ll receive the quantity of a preparation calculated for a maximum of 30 days of reception. To your recipe a yellow self-glued label must be attached. If there is such label on the recipe, contact your doctor. The pharmacy has no right to release a preparation without presence of such label.
It is necessary to wash down each doze with a full glass of water. It will allow to avoid irritation of a gullet by a medicine. For the same reason, swallow a preparation entirely, not chewing.
Accept Isotretinoin twice a day, washing down with water or milk if other is not recommended your doctor.
Accept all Isotretinoin prescribed to you, even if improvement of a condition is observed. In the beginning of reception of a preparation a temporary deterioration of acne is possible, but after that improvement should be observed. For obtaining the best results finish a complete course of a preparation registered by the doctor. Probably it is required more than one course of treatment by Isotretinoin .
The Doctor can recommend to you to make the analysis of blood and to pass other medical examinations during treatment by a preparation, to reveal by-effects of a preparation.Because of serious by-effects which can be caused by reception of the given preparation, do not pass it to other persons.
Store Isotretinoin at a room temperature far from sources of heat and moisture.
What will be, if I miss a reception of a preparation?
Accept a medicine immediately when you recollect. In case if time of the next reception of a preparation already approaches, it is not necessary to accept the missed doze. It is necessary to wait for the next reception of a preparation. Do not accept a double doze of a medicine. What will occur in case of overdose of a preparation?
in case of possible overdose immediately address to the doctor.
to the symptoms of overdose are referred the nausea, a pain in a stomach area, reddening of face, irritation of lips, a headache and dizziness.
Safety measures
do not accept the vitamin additives containing vitamin A during treatment with Isotretinoin . It can lead to strengthening of collateral actions.
do not hand over donor blood during reception Isotretinoin and not less than month after the termination of reception of a preparation. The blood which has been handed over during reception Isotretinoin , can be poured to the pregnant woman and harm its child.
do not apply wax procedures to removal of hair on skin, and also refrain from grinding skin (such as dermabrasion or laser procedures) during reception of Isotretinoin and within six months after its termination to avoid occurrence of scars.
Avoid being under sunlight, and also influences of ultra-violet beams during the reception Isotretinoin . Isotretinoin can raise sensitivity of skin to solar beams that may lead to serious solar burns.
Be careful while driving the car at night. Isotretinoin can affect ability to see at night. Deterioration of night sight may suddenly come. What are the possible by-effects of Isotretinoin ?
In case of occurrence of any of serious by-effects from listed below it is necessary to stop reception of a preparation immediately and urgently to address to the doctor:
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- allergic reaction (the complicated breath; narrowing of respiratory ways; a hypostasis of lips, face, language; or a rash);
- deterioration of sight (especially at night);
- painful dryness of eyes;
- depression, including feeling of despondency, irritability, frustration of a dream, feeling of excessive tiredness, impossibility to concentrate, loss of appetite, and/or suicide ideas or other mental problems;
- stomach ache, pain in breasts or intestines;
- anorectal bleeding or hemorrhagic diarrhea;
- painful swallowing;
- heartburn;
- yellowing of skin or darkening of urine;
- strong headaches or dizziness;
- convulsions;
- nausea;
- pains in joints or muscles;
- deterioration of hearing;
- heavy breathing;
- loss of consciousness;
- strong thirst or urination;
- muffled speech;
- swelling of legs;
- raised level of cholesterol or triglyceride in blood (it is defined by means of blood test).
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There can be other by-effects which have been not stated in the given application guide. It is necessary to inform the doctor about any unusual by-effects, particularly those that cause your anxiety.
