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Restoril

The principal mechanism of sleeping effect is the depression of cells of reticular formation of the brain stem. Restoril reduces the impact of emotional, vegetative and motor stimuli, distorting the mechanism of falling asleep. The direct inhibition of motor nerves and muscle function is also possible. The drug has little impact on the productive symptoms of psychotic genesis (acute delusional, hallucinatory and affective disorders), rarely observed reduction of emotional tension and delusional disorders. Restoril improves mood, relieves falling asleep and increases appetite. It is effective in treatment of cardialgia and headache of neurotic genesis.

Indications for use

Neurosis and psychopathy, accompanied by anxiety, fear, emotional tension, depressive and hypochondriac syndrome. Neurasthenia, involutional depression. Insomnia.

Dosage

Adults- from 7.5 to 30 mg. The dose can be taken at once 30 minutes before bed or 2.5-10 mg 3 times a day. Maximal dose: 20 mg 3 times a day.

Contraindications

Coma, shock, acute alcohol intoxication with the depression of vital functions, drug intoxications, which have depressant effects on CNS (narcotic, soporific and psychotropic drugs), myasthenia gravis, angle-closure glaucoma (acute attack or predisposition), severe COPD (progressive degree of respiratory failure), acute respiratory failure, severe depression (with possible suicidal tendencies), pregnancy, lactation (breastfeeding), children and teenagers under 18 (safety and efficiency are not defined), hypersensitivity to temazepam.

Pregnancy and lactation

Restoril is contraindicated during pregnancy and lactation (breastfeeding).

Influence on the fetus: teratogenicity (especially in I trimester), CNS depression, respiratory failure and depression of sucking reflex in newborns, whose mothers took temazepam.

Special indications

Patients with renal or respiratory failure, cerebral or spinal ataxia, hyperkinesis, drug addiction in anamnesis, prone to the substance abuse, organic brain diseases, psychosis (possible paradoxical reactions), hypoproteinemia, sleep apnea (diagnosed or estimated), and old age must take the drug with caution.

Alcohol consumption is prohibited during the treatment.

Impact on the capacity of driving vehicles and management of mechanisms.

The patients taking Restoril should refrain from the potentially dangerous activities that require increased attention and fast psychomotor reactions.

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